Prone Positioning in Viral Bronchiolitis—Back to the Back?

Дата публикации: 28-07-2026 00:00:00

Acute viral bronchiolitis is the most common diagnosis in US children’s hospitals, and respiratory failure is the costliest diagnosis across all pediatric acute care. Despite the prevalence of this condition and its impact on children, families, and health systems, evidence-based treatments for acute bronchiolitis in hospitalized children are few and guidelines largely recommend against most interventions. In this issue of JAMA, Baudin and colleagues for the PROPOSITIS Investigators evaluated a promising but understudied option: prone positioning. In a well-designed randomized clinical trial (RCT) conducted from 2021 to 2023, the authors enrolled 451 infants younger than 6 months with viral bronchiolitis who were receiving high-flow nasal cannula (HFNC) support. The primary end point of the study was escalation of care to noninvasive or invasive positive pressure ventilation (notably, only 3 children in the cohort were intubated). The primary intention-to-treat analysis did not reach statistical significance—with an odds ratio for escalation with prone positioning of 0.66 (95% CI, 0.40-1.07)—which was surprising given that their pilot physiological study suggested that prone positioning either improves effort of breathing or has negligible impact.

Схожие новости

#	Наименование новости	Тональность	Информативность	Дата публикации
1	Considerations Regarding Valved Holding Chamber Efficiency	0	7.7	01-08-2026
2	Considerations Regarding Valved Holding Chamber Efficiency	0	12.7	01-08-2026
3	Posture and postural balance in people aged 6-39 years with asthma: a systematic review [version 1; peer review: awaiting peer review]	0	9.92	12-08-2026
4	Capturing Indoor Movement: A Classroom Video Approach to Assessing Preschoolers’ Physical Activity	0	8.59	06-08-2026
5	Kind nach Unfall in Krankenhaus	0	5	30-06-2026
6	Modeling Oxygen Saturation Targets, Mortality, and Retinopathy in Preterm Infants	0	7.78	21-07-2026
7	В Петербурге нашли истощенного младенца	0	0	13-09-2018
8	Свисток в бронхах едва ни убил ребёнка во время игры	-2	6	13-07-2026
9	Эксперт сообщил, что постковидный синдром у детей фиксируется в 10-30% случаев	0	0	09-02-2022
10	Не пациент на УЗИ, а УЗИ к пациенту: в Сеченовском Университете обсудили новый метод проведения ультразвукового исследования	0	5	19-06-2026

Классификация: . Схожих патентов: 0. Схожих новостей: 10. Тональность: 0. Информативность: 8.78. Источник: jamanetwork.com.